Return to Main MenuContact Us
Consider the Burden of Chronic Kidney Disease–related Anemia
According to the American Society of Nephrology and the National Kidney Foundation:
Chronic Kidney Disease (CKD) Is Now an Epidemic1,2
| Prevalence of Earlier-stage CKD Has Risen Sharply*3,4 |
| Severity |
World Health Organization |
National Cancer Institute |
| |
Prevalence, % (95% CI) in Cross-sectional Analysis |
| CKD Stage |
1988-1994 (N = 15,488) |
1999-2004 (N = 13,233) |
| 1 (GFR ≥ 90 mL/min/1.73 m2) |
1.71 (1.28-2.18) |
1.78 (1.35-2.25) |
| 2 (GFR of 60 to 89 mL/min/1.73 m2) |
2.70 (2.17-3.24) |
3.24 (2.61-3.88) |
| 3 (GFR of 30 to 59 mL/min/1.73 m2) |
5.42 (4.89-5.95) |
7.69 (7.02-8.36) |
| 4 (GFR of 15 to 29 mL/min/1.73 m2) |
0.21 (0.15-0.27) |
0.35 (0.5-0.45) |
| Total |
10.03 (9.16-10.91) |
13.07 (12.04-14.10) |
Adapted from Coresh et al.4
CI = confidence interval; GFR = glomerular filtration rate.
- Stage 5 CKD is reached when GFR falls below 15 mL/min/1.73 m2 or if patient requires dialysis3
Anemia Is One of the Common Complications of CKD†5
Adapted with permission from McClellan et al.5
Hb = hemoglobin.
- There were 5 times more anemic stage 3 patients than anemic stage 5 patients‡5
- Other complications of CKD include cardiovascular and bone disease and malnutrition3
*Results from a cross-sectional analysis of the most recent National Health and Nutrition Examination Survey nationally representative surveys of noninstitutionalized adults ≥ 20 years of age (1988-1994 [N = 15,488] and 1999-2004 [N = 13,233]).4
†Results from a cross-sectional multicenter survey in patients with CKD (N = 5222).5
‡When comparing 41.6% of 2832 patients versus 75.5% of 298 patients (see bar chart).
1.Szczech LA, Harmon W, Hostetter TH, et al. World Kidney Day 2009: problems and challenges in the emerging epidemic of kidney disease. J Am Soc Nephrol. 2009;20:453-464.
2.National Kidney Foundation. Chronic kidney disease (CKD): the facts about chronic kidney disease (CKD). http://www.kidney.org/kidneydisease/ckd/index.cfm#facts. Accessed June 30, 2010.
3.National Kidney Foundation. K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Am J Kidney Dis. 2002;39(2 suppl 1):S1-S266.
4.Coresh J, Selvin E, Stevens LA, et al. Prevalence of chronic kidney disease in the United States. JAMA. 2007;298(17):2038-2047.
5.McClellan W, Aronoff SL, Bolton WK, et al. The prevalence of anemia in patients with chronic kidney disease. Curr Med Res Opin. 2004;20(9):1501-1510.